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Bone Marrow Transplant: Benefits & Risks

Bone marrow transplant is a process that infuses healthy blood-forming stem cells inside your body to replace damaged or diseased bone marrow. Bone marrow transplant is also known as stem cell transplant. 

A stem cell transplant is required when the bone marrow stops working and does not produce adequate healthy blood cells.


Bone marrow transplant uses two types of marrow one from our own body (autologous transplant) and the other being from donors (allogeneic transplant).



Uses of Bone Marrow:


It can be used:

  • During chemotherapy or radiation. It helps in replacing the damaged bone marrow during high doses of treatment. 

  • Replacing deceased bone marrow.

  • Replacing marrow for killing cancer cells directly. 


Bone marrow transplant benefits hugely to people with a range of both cancerous (malignant) and noncancerous (benign) diseases, including: 


  • Acute leukemia

  • Adreno-leuko-dystrophy

  • Aplastic anemia

  • Bone marrow failure syndrome

  • Chronic leukemia

  • Hemoglobinopathies

  • Hodgkin’s lymphoma

  • Non - Hodgkin's lymphoma

  • Immune deficiency

  • Hereditary Genetic disorder 

  • Multiple myeloma

  • Neuroblastoma

  • Plasma cell disorder

  • POEMS syndrome

  • Primary amyloidosis


Risks Associated With Bone Marrow Transplant:


With a positive side, bone marrow transplant has a negative side also. 

Some people may experience some mild problems after a bone marrow transplant, while others may face serious complications which may require treatment or may be hospitalized. In extremely rare cases it can be life-threatening too.  


The risk factor depends upon many reasons, including the condition or disease which prompted you for a bone marrow transplant, type of transplant, age, overall health, or hereditary genes.


A few of the possibilities are:


  • Graft versus host disease (in allogeneic transplant only): Potential risk when it comes from a donor. When the graft is done, the tissue might think of your organs and tissues as an enemy and start killing it.  

  • Transplant failure

  • Organ damage

  • Infection

  • Cataracts

  • Infertility

  • New forms of cancer

  • Death


Your doctor can tell you best about the risk which you will encounter after the transplant. After getting all the information, a patient can decide whether to opt for treatment or not. 


The department for bone marrow transplant at Sarvodaya Centre for Cancer Care is the place to be for the procedure. Their advancement in the procedure, state of art facilities, and their team of best specialists for transplant in Faridabad, make them one of the best bone marrow transplant centres in the entire NCR region. The department specializes in taking necessary pre and post-care of patients.


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